5-Methoxy-2,N,N-trimethyltryptamine (5-MeO-2,N,N-TMT, 5-MeO-TMT) is a psychoactive drug of the tryptamine chemical class which acts as a psychedelic. It was first synthesized by Alexander Shulgin and reported in his book TiHKAL (\"Tryptamines i Have Known And Loved\"). 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75-150mg orally, but these are relatively mild compared to those of other similar compounds. This suggests that while the methyl group on the 2-position of the molecule has impaired the binding of metabolic enzymes like monoamine oxidase (MAO), it is also interfering with binding to and/or activation of the serotonin 5-HT2A receptor, the target responsible for mediating the hallucinogenic effects of such compounds.

CAS：67292-68-6
中文别名：
英文别名：2-methyl-5-methoxy-N,N-dimethyltryptamine;Methyl-2-methoxy-5-N-dimethyltryptamine;4365 CT;
分子式：C14H20N2O
分子量：232.321
精确质量：232.158
Psa：28.26
Logp：2.589

UNII：XZ2CCP18I2

密度：1.079g/cm3
沸点：383.7ºC at 760 mmHg
闪点：185.8ºC
折射率：1.589