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化合物简介
Procarbazine (Matulane (US), Natulan (Canada), Indicarb (India) is an antineoplastic chemotherapy drug for the treatment of Hodgkin's lymphoma and certain brain cancers (such as glioblastoma multiforme).
基本信息
CAS：671-16-9
中文别名：甲肼苄甲酰异丙胺;N-异丙基-4-((2-甲基肼)甲基)苯甲酰胺;
英文别名：Natulan;Procarbazine;N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide;Procarbazinum;Ibenzmethyzin;Procarbazina;N-Isopropyl-4-((2-methylhydrazinyl)methyl)benzamide;4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;[4-(2-methyl-hydrazino)-methyl-benzoic acid-isopropylamide];Procarbazin;N-isopropyl-4-[(N\'-methylhydrazino)methyl]benzamide;
分子式：C12H19N3O
分子量：221.299
精确质量：221.153
Psa：53.16
Logp：2.2215
中文别名：甲肼苄甲酰异丙胺;N-异丙基-4-((2-甲基肼)甲基)苯甲酰胺;
英文别名：Natulan;Procarbazine;N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide;Procarbazinum;Ibenzmethyzin;Procarbazina;N-Isopropyl-4-((2-methylhydrazinyl)methyl)benzamide;4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;[4-(2-methyl-hydrazino)-methyl-benzoic acid-isopropylamide];Procarbazin;N-isopropyl-4-[(N\'-methylhydrazino)methyl]benzamide;
分子式：C12H19N3O
分子量：221.299
精确质量：221.153
Psa：53.16
Logp：2.2215
编号系统
UNII：35S93Y190K
物化性质
密度：1.035 g/cm3
沸点：384.6ºC at 760 mmHg
闪点：148.9ºC
稳定性：Stable in light, slowly oxidized in air. Hydrochloride stable at room temperature (in presence of oxygen, oxidn is accelerated by incr temperature).
储存条件：Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
沸点：384.6ºC at 760 mmHg
闪点：148.9ºC
稳定性：Stable in light, slowly oxidized in air. Hydrochloride stable at room temperature (in presence of oxygen, oxidn is accelerated by incr temperature).
储存条件：Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
安全信息
海关编码：2928000090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
Mass spectrum (electron ionization)
