Forskolin (coleonol) is a labdane diterpene that is produced by the Indian Coleus plant (Coleus forskohlii). Forskolin is commonly used as a tool in biochemistry to raise levels of cyclic AMP (cAMP) in the study and research of cell physiology. Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second messenger necessary for the proper biological response of cells to hormones and other extracellular signals. It is required for cell communication in the hypothalamus/pituitary gland axis and for the feedback control of hormones. Cyclic AMP acts by activating cAMP-sensitive pathways such as protein kinase A and Epac.

CAS：66428-89-5
中文别名：
英文别名：Flavopirodol;(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihydroxy-3,4a,7,7,10a -pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl ace tate;(+/-)-Flavopiridol;Alvocidib;vopiridol(Alvocidib);Alvocidib,Free Base;
分子式：C22H34O7
分子量：410.501
精确质量：410.23
Psa：113.29
Logp：1.5199

熔点：277ºC