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化合物简介
N-Methyl-D-aspartic acid or N-Methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors (such as those for AMPA and kainate). NMDA receptors are particularly important when they become overactive during withdrawal from alcohol as this causes symptoms such as agitation and, sometimes, epileptiform seizures.
基本信息
CAS:6384-92-5
中文别名:N-甲基-D-天冬氨酸水合物;阿托莫西汀盐酸盐.盐酸托莫西汀;(R)-2-(甲基氨基)丁二酸;N-甲基-D-天门冬氨酸;N-甲基-D-天(门)冬氨酸;N-甲基-D-天门冬胺基乙酸;
英文别名:(2R)-2-(methylamino)butanedioic acid;
分子式:C5H9NO4
分子量:147.129
精确质量:147.053
Psa:86.63
Logp:-0.4754
中文别名:N-甲基-D-天冬氨酸水合物;阿托莫西汀盐酸盐.盐酸托莫西汀;(R)-2-(甲基氨基)丁二酸;N-甲基-D-天门冬氨酸;N-甲基-D-天(门)冬氨酸;N-甲基-D-天门冬胺基乙酸;
英文别名:(2R)-2-(methylamino)butanedioic acid;
分子式:C5H9NO4
分子量:147.129
精确质量:147.053
Psa:86.63
Logp:-0.4754
编号系统
MDL号:MFCD00004226
物化性质
外观与性状:白色固体
密度:1.343 g/cm3
沸点:258.2ºC at 760 mmHg
熔点:187-192 °C
闪点:110ºC
折射率:-15 ° (C=2, H2O)
水溶解性:slightly soluble
储存条件:Store at RT.
密度:1.343 g/cm3
沸点:258.2ºC at 760 mmHg
熔点:187-192 °C
闪点:110ºC
折射率:-15 ° (C=2, H2O)
水溶解性:slightly soluble
储存条件:Store at RT.
安全信息
RTECS号:CI9457000
安全说明:S22-S24/25
WGK Germany:3
海关编码:2942000000
安全说明:S22-S24/25
WGK Germany:3
海关编码:2942000000
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