An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

CAS：633-65-8
中文别名：盐酸黄连素.盐酸小檗硷;小檗碱;黄莲素盐酸盐水合物;盐酸黄连素;盐酸钡;
英文别名：Berberine hydrochloride;berberine hydrochloride;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride;5,6-dihydro-9,10-dimethoxy-1,3-benzodioxolo[5,6-a]benzo[g]quinolizinium chloride (1:1);9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium chloride;
分子式：C20H18ClNO4
分子量：371.814
精确质量：371.092
Psa：40.8
Logp：0.1003

MDL号：MFCD00011939

外观与性状：黄色结晶粉末
密度：1.654g/cm3
熔点：200ºC
稳定性：Stable under normal temperatures and pressures.
储存条件：低温通风低干燥,与库房食品原料分开存放

RTECS号：DR9866400
安全说明：S24/25
危险类别码：R20/21/22
WGK Germany：2
危险品运输编码：UN 1544
海关编码：3003409000
危险类别：6.1(b)
包装等级：III
危险品标志：Xn

用途
抗菌药，主要用于肠道类疾病的治疗。主要用于治疗胃肠炎、细菌性痢疾等肠道感染、眼结膜炎、化脓性中耳炎等有效。近来还发现本品有阻断α-受体，抗心律失常作用。