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化合物简介
Adapromine is an antiviral drug of the adamantane group related to amantadine (1-aminoadamantane), rimantadine (1-(1-aminoethyl)adamantane), and memantine (1-amino-3,5-dimethyladamantane) that is marketed in Russia for the treatment and prevention of influenza. It is an alkyl analogue of rimantadine and is similar to rimantadine in its antiviral activity but possesses a broader spectrum of action, being effective against influenza viruses of both type A and B. Strains of type A influenza virus with resistance to adapromine and rimantadine and the related drug deitiforine were encountered in Mongolia and the Soviet Union in the 1980s.
基本信息
CAS:60196-90-9
中文别名:
英文别名:Adapromine;1-Adamantan-1-yl-propylamine;1-adamantanylpropylamine;
分子式:C13H23N
分子量:193.328
精确质量:193.183
Psa:26.02
Logp:3.6404
中文别名:
英文别名:Adapromine;1-Adamantan-1-yl-propylamine;1-adamantanylpropylamine;
分子式:C13H23N
分子量:193.328
精确质量:193.183
Psa:26.02
Logp:3.6404
编号系统
MDL号:MFCD01838799
物化性质
沸点:262.3ºC at 760 mmHg
闪点:108.3ºC
闪点:108.3ºC
安全信息
海关编码:2921300090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
