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  • 2-(3,5-二氯苯基)-6-苯并恶唑甲酸

    tafamidis

化合物简介

Tafamidis (INN, or Fx-1006A, trade name Vyndaqel) is a drug for the amelioration of transthyretin-related hereditary amyloidosis (also familial amyloid polyneuropathy, or FAP), a rare but deadly neurodegenerative disease. The drug was approved by the European Medicines Agency in November 2011 and by the Japanese Pharmaceuticals and Medical Devices Agency in September 2013.

基本信息

CAS:594839-88-0
中文别名:2-(3,5-二氯苯基)-6-苯并噁唑羧酸;
英文别名:TAFAMIDIS;8FG9H9D31J;UNII-8FG9H9D31J;FX-1006;3MI;2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid;
分子式:C14H7Cl2NO3
分子量:308.116
精确质量:306.98
Psa:63.33
Logp:4.4998

编号系统

UNII:8FG9H9D31J

物化性质

密度:1.53

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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