化学科研者一站式服务平台
化合物简介
Tafamidis (INN, or Fx-1006A, trade name Vyndaqel) is a drug for the amelioration of transthyretin-related hereditary amyloidosis (also familial amyloid polyneuropathy, or FAP), a rare but deadly neurodegenerative disease. The drug was approved by the European Medicines Agency in November 2011 and by the Japanese Pharmaceuticals and Medical Devices Agency in September 2013.
基本信息
CAS:594839-88-0
中文别名:2-(3,5-二氯苯基)-6-苯并噁唑羧酸;
英文别名:TAFAMIDIS;8FG9H9D31J;UNII-8FG9H9D31J;FX-1006;3MI;2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid;
分子式:C14H7Cl2NO3
分子量:308.116
精确质量:306.98
Psa:63.33
Logp:4.4998
中文别名:2-(3,5-二氯苯基)-6-苯并噁唑羧酸;
英文别名:TAFAMIDIS;8FG9H9D31J;UNII-8FG9H9D31J;FX-1006;3MI;2-(3,5-Dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid;
分子式:C14H7Cl2NO3
分子量:308.116
精确质量:306.98
Psa:63.33
Logp:4.4998
编号系统
UNII:8FG9H9D31J
物化性质
密度:1.53
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
