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化合物简介
Benzilylcholine mustard (N-2-chloroethyl-N-methyl 2-aminoethyl benzilate) is a modified version of acetylcholine, so named because after cyclization in solution it forms an iminium derivative that is structurally similar to benzilylcholine. It is well known for being an irreversible antagonist of the muscarinic acetylcholine receptor. It has been used in pharmacological experiments investigating the relationship between receptor occupancy and response. It was also one of the tools in characterization of the muscarinic acetylcholine receptor.
基本信息
CAS:5746-42-9
中文别名:
英文别名:Benzilylcholine mustard;N-2-chloroethyl-N-methyl 2-aminoethyl benzilate;
分子式:C19H22ClNO3
分子量:347.836
精确质量:347.129
Psa:49.77
Logp:2.6363
中文别名:
英文别名:Benzilylcholine mustard;N-2-chloroethyl-N-methyl 2-aminoethyl benzilate;
分子式:C19H22ClNO3
分子量:347.836
精确质量:347.129
Psa:49.77
Logp:2.6363
编号系统
物化性质
密度:1.206g/cm3
沸点:407.3ºC at 760mmHg
闪点:200.1ºC
折射率:1.571
沸点:407.3ºC at 760mmHg
闪点:200.1ºC
折射率:1.571
安全信息
生产方法及用途
合成路线
-
参考文献
Ioffe,D.V.; Kuznetsov,S.G. J. Gen. Chem. USSR (Engl. Transl.), 1964 , vol. 34, p. 1336 - 1341,1335 - 1339
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图谱
1H NMR : Predict
13C NMR : Predict



