Trimethylsilylpropanoic acid (TMSP or TSP) is a chemical compound containing a trimethylsilyl group. It is used as internal reference in the NMR spectrum nuclear magnetic resonance for aqueous solvents (e.g. D2O). For that use it is often deuterated (3-(trimethylsilyl)-2,2,3,3-tetradeuteropropionic acid or TMSP-d4). Other internal references that are frequently used in NMR experiments are DSS and tetramethylsilane.

CAS：5683-30-7
中文别名：3-(三甲基甲硅烷基)丙酸;
英文别名：3-(Trimethylsilyl)propanoic acid;trimethylsilyl propionic acid;Propanoic acid,3-(trimethylsilyl);3-(Trimethylsilyl)propionic acid;3-trimethylsilylpropanoic acid;2-Silapentan-5-oic acid,2,2-dimethyl;3-trimethylsilylpropanoate;4,4-dimethyl-4-silapentanoic acid;EINECS 227-145-4;Propionic acid,3-(trimethylsilyl);
分子式：C6H14O2Si
分子量：146.26
精确质量：146.076
Psa：37.3
Logp：1.7993

EINECS号：227-145-4

外观与性状：透明至稻黄色液体带有独特的温和气味
密度：0.926g/cm3
沸点：223.6ºC at 760 mmHg
熔点：<0ºC
闪点：89ºC
折射率：1.428

安全说明：S26; S36/37/39
危险类别码：R36/37/38