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化合物简介
N-(2-Hydroxyethyl)-D-glucamine, is a key intermediate for the synthesis of Miglitol, which is a potent α-glucosidase inhibitor, used as a new antidiabetic drug.
基本信息
CAS：54662-27-0
中文别名：
英文别名：1-desoxy-1-(2-hydroxy-ethylamino)-D-glucitol;1-(2-hydroxy-ethyl)-6-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one;1-(2-Hydroxy-aethyl)-6-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-on;1-(2-Hydroxy-aethylamino)-1-desoxy-D-glucit;1-(2-hydroxyethyl)-6-methyl-1,2-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one;N-(2-Hydroxy-aethyl)-D-glucamin;N-(2-Hydroxyethyl)-D-glucamine;1-deoxy-1-(2-hydroxyethylamino)-D-glucitol;1-(2-hydroxy-ethylamino)-1-deoxy-D-glucitol;
分子式：C8H19NO6
分子量：225.24
精确质量：225.121
Psa：133.41
Logp：-3.6049
中文别名：
英文别名：1-desoxy-1-(2-hydroxy-ethylamino)-D-glucitol;1-(2-hydroxy-ethyl)-6-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one;1-(2-Hydroxy-aethyl)-6-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-on;1-(2-Hydroxy-aethylamino)-1-desoxy-D-glucit;1-(2-hydroxyethyl)-6-methyl-1,2-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one;N-(2-Hydroxy-aethyl)-D-glucamin;N-(2-Hydroxyethyl)-D-glucamine;1-deoxy-1-(2-hydroxyethylamino)-D-glucitol;1-(2-hydroxy-ethylamino)-1-deoxy-D-glucitol;
分子式：C8H19NO6
分子量：225.24
精确质量：225.121
Psa：133.41
Logp：-3.6049
编号系统
物化性质
密度：1.444g/cm3
沸点：565.2ºC at 760 mmHg
闪点：277.2ºC
折射率：1.577
沸点：565.2ºC at 760 mmHg
闪点：277.2ºC
折射率：1.577
安全信息
海关编码：2922199090
生产方法及用途
合成路线
-
参考文献
du Pont de Nemours and Co. Patent: GB426062 ; Full Text Show Details du Pont de Nemours and Co. Patent: US2016962 , 1932 ; Full Text Show Details du Pont de Nemours and Co. Patent: US1994467 , 1932 ; Full Text Show Details du Pont de Nemours and Co. Patent: US2016963 , 1932 ;
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
