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化合物简介
2-Arachidonoylglycerol (2-AG) is an endocannabinoid, an endogenous agonist of the CB1 receptor. It is an ester formed from the omega-6 fatty acid arachidonic acid and glycerol. It is present at relatively high levels in the central nervous system, with cannabinoid neuromodulatory effects. It has been found in maternal bovine and human milk. The chemical was first described in 1994-1995, although it had been discovered some time before that. The activities of Phospholipase C (PLC) and diacylglycerol lipase (DAGL) mediate its formation. 2-AG is synthesized from arachidonic acid-containing diacylglycerol (DAG).
基本信息
CAS:53847-30-6
中文别名:
英文别名:1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Arachidonyl Glycerol;2-Arachidonyl glycerol;
分子式:C23H38O4
分子量:378.545
精确质量:378.277
Psa:66.76
Logp:5.0285
中文别名:
英文别名:1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Arachidonyl Glycerol;2-Arachidonyl glycerol;
分子式:C23H38O4
分子量:378.545
精确质量:378.277
Psa:66.76
Logp:5.0285
编号系统
PubChem号:24891388
MDL号:MFCD01862600
MDL号:MFCD01862600
物化性质
外观与性状:液体
密度:0.992 g/cm3
沸点:508.6ºC at 760 mmHg
闪点:2°C
折射率:1.507
储存条件:-20ºC
密度:0.992 g/cm3
沸点:508.6ºC at 760 mmHg
闪点:2°C
折射率:1.507
储存条件:-20ºC
安全信息
安全说明:S26-S36/37
WGK Germany:2
危险类别码:R11
海关编码:2916190090
危险品运输编码:UN 1648 3/PG 2
危险品标志:Xn; F
WGK Germany:2
危险类别码:R11
海关编码:2916190090
危险品运输编码:UN 1648 3/PG 2
危险品标志:Xn; F
生产方法及用途
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图谱
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