Pirfenidone (INN, BAN) is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II.

CAS：53179-13-8
中文别名：5-甲基-1-苯基-2-(1H)-吡啶酮;吡非尼酮;
英文别名：Pirfenidone;5-Methyl-N-phenyl-2-1H-pyridone;5-methyl-1-phenyl-1H-pyridin-2-one;5-Methyl-1-phenyl-2-(1H)-pyridone;5-methyl-1-phenyl-pyridin-2-one;amr-69;5-Methyl-1-phenylpyridin-2(1H)-one;TORASEMIDETECHPIRFENIDONE;5-methyl-1-phenyl-2-pyridone;5-Methyl-1-phenyl-2-pyridone;S-7701;
分子式：C12H11NO
分子量：185.222
精确质量：185.084
Psa：22.0
Logp：2.1459

MDL号：MFCD00866047

密度：1.137 g/cm3
沸点：329.1ºC at 760 mmHg
熔点：96-97ºC
闪点：152.7ºC
折射率：1.592
储存条件：Store at RT

RTECS号：UV1148200
安全说明：S36
危险类别码：R22
WGK Germany：3
海关编码：2933399090
危险品标志：Xn
信号词：Warning
危险标志：GHS07
危险性描述：H302

用途
主要用于治疗特发性肺纤维化,抑止肺部炎症和过量胶原沉积。