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  • 甲羟孕酮

    medroxyprogesterone

化合物简介

Medroxyprogesterone (INN, BAN), also known as 17α-hydroxy-6α-methylprogesterone, and abbreviated as MP, is a steroidal progestin drug which was never marketed for use in humans. An acylated derivative, medroxyprogesterone acetate (MPA), is clinically used as a pharmaceutical medicine. Compared to MPA, MP is over two orders of magnitude less potent as a progestogen. As such, MP itself is not used clinically, though it has seen limited use in veterinary medicine under the trade name Controlestril in France. In addition, it is a metabolite of MPA.

基本信息

CAS:520-85-4
中文别名:6Alpha-甲基-17Alpha-羟孕酮;甲孕酮;17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione;6α-甲基-17α-羟孕酮;
英文别名:Medroxyprogesteron;Medroxyprogesteronum;Hydroxymethylprogesterone;17alpha-Hydroxy-6alpha-methylprogesterone;(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;Medroxyprogesterone;Medroxy Progesterone;Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6α)-;17-Hydroxy-6alpha-methylprogesterone;Medroxiprogesteronum;Medrossiprogesterone;Farlutal;
分子式:C22H32O3
分子量:344.488
精确质量:344.235
Psa:54.37
Logp:4.0844

编号系统

UNII:HSU1C9YRES

物化性质

密度:1.13g/cm3
沸点:488ºC at 760mmHg
熔点:220-223.5ºC
闪点:263ºC
折射率:1.538
储存条件:Refrigerator

安全信息

危险类别码:R48; R63; R68
危险品标志:Xn
危险标志:GHS08
危险性描述:H361
信号词:Warning
危险性防范说明:P281

生产方法及用途

合成路线

上游原料

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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