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化合物简介
This substance is listed as a known human carcinogen. It is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic.
基本信息
CAS:52-24-4
中文别名:三亚乙基硫代磷酰胺;噻替哌;1,1\',1\"-硫次膦基三氮丙啶;三(1-吖丙啶基)硫代磷酰;塞替派;
英文别名:N,N‘,N’‘-Triethylenethiophosphoramide;Triethylenethiophosphoramide;Tri(1-aziridinyl)phosphine sulfide;1,1’,1″-phosphinothioylidynetris[aziridine];N,N\',N\'\'-Triethylenethiophosphoramide;Phosphine, tris(1-aziridinyl)-, sulfide;Tris(aziridinyl)phosphine sulfide;Tri(aziridin-1-yl)phosphine sulfide;1,1’,1″-phosphorothioyltris(aziridine);tris(1-aziridinyl)phosphine sulfide;phosphorothioic tri(ethyleneamide);Thiotepa;1,1\',1\'\'-Phosphorothioyltriaziridine;
分子式:C6H12N3PS
分子量:189.218
精确质量:189.049
Psa:50.93
Logp:0.622
中文别名:三亚乙基硫代磷酰胺;噻替哌;1,1\',1\"-硫次膦基三氮丙啶;三(1-吖丙啶基)硫代磷酰;塞替派;
英文别名:N,N‘,N’‘-Triethylenethiophosphoramide;Triethylenethiophosphoramide;Tri(1-aziridinyl)phosphine sulfide;1,1’,1″-phosphinothioylidynetris[aziridine];N,N\',N\'\'-Triethylenethiophosphoramide;Phosphine, tris(1-aziridinyl)-, sulfide;Tris(aziridinyl)phosphine sulfide;Tri(aziridin-1-yl)phosphine sulfide;1,1’,1″-phosphorothioyltris(aziridine);tris(1-aziridinyl)phosphine sulfide;phosphorothioic tri(ethyleneamide);Thiotepa;1,1\',1\'\'-Phosphorothioyltriaziridine;
分子式:C6H12N3PS
分子量:189.218
精确质量:189.049
Psa:50.93
Logp:0.622
编号系统
MDL号:MFCD00145452
物化性质
外观与性状:白色晶体或粉末
密度:1.5g/cm3
沸点:270.2ºC at 760mmHg
熔点:54-57 °C
闪点:117.2ºC
折射率:1.708
水溶解性:19 G/100 ML (25 ºC)
稳定性:Stable. Incompatible with strong oxidizing agents.
储存条件:2-8ºC
密度:1.5g/cm3
沸点:270.2ºC at 760mmHg
熔点:54-57 °C
闪点:117.2ºC
折射率:1.708
水溶解性:19 G/100 ML (25 ºC)
稳定性:Stable. Incompatible with strong oxidizing agents.
储存条件:2-8ºC
安全信息
RTECS号:SZ2975000
安全说明:53-22-26-36/37/39-45-36/37-28
WGK Germany:3
危险类别码:R28; R45; R46
海关编码:2933990090
危险品运输编码:UN 2811 6.1/PG 2
危险类别:6.1(a)
包装等级:II
危险品标志:T+
危险标志:GHS06, GHS08
危险性描述:H300; H350
危险性防范说明:P201; P264; P301 + P310; P308 + P313
信号词:Danger
安全说明:53-22-26-36/37/39-45-36/37-28
WGK Germany:3
危险类别码:R28; R45; R46
海关编码:2933990090
危险品运输编码:UN 2811 6.1/PG 2
危险类别:6.1(a)
包装等级:II
危险品标志:T+
危险标志:GHS06, GHS08
危险性描述:H300; H350
危险性防范说明:P201; P264; P301 + P310; P308 + P313
信号词:Danger
生产方法及用途
用途
对乳腺癌和卵巢癌有较好的疗效
对乳腺癌和卵巢癌有较好的疗效