Tetrandrine a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It has anti-inflammatory, immunologic and antiallergenic effects. It inhibits the degranulation of mast cells. It has a \"Quinidine like\" anti-arrhythmic effect. It has been isolated from Stephania tetrandra S Moore, and other Chinese and Japanese herbs. It has vasodilatory properties and can therefore reduce blood pressure. Tetrandrine may have potential use for the treatment of liver disease and liver cancer. Tetrandrine has potential therapeutic value to prevent excess scarring/fibrosis in conjunctiva following trabeculectomy or in patients with severe conjunctival inflammation. Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis. Tetrandrine has also been shown to inhibit entry of Ebola virus into host cells in vitro and showed therapeutic efficacy against Ebola in preliminary studies on mice.

CAS：518-34-3
中文别名：(S,S)-(+)-粉防已碱;(1β)-6,6\',7,12-Tetramethoxy-2,2\'-dimethylberbaman;粉防己碱;
英文别名：sinomeninea;TETRANDRIN;Tetrandrine;hanfangchin A;Trandrine;fanchinine;Conba;6,6\',7,12-tetramethoxy-2,2\'-dimethyl-berbaman;Jinake;
分子式：C38H42N2O6
分子量：622.75
精确质量：622.304
Psa：61.86
Logp：7.0382

UNII：29EX23D5AJ

外观与性状：白色固体
密度：1.17 g/cm3 (20ºC)
沸点：710.5ºC at 760 mmHg
熔点：219-222ºC
闪点：175.8ºC
折射率：1.585
稳定性：Stable at normal temperatures and pressures.
储存条件：Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 20ºC.

安全说明：S22-S24/25
危险类别码：R36/37/38
海关编码：2942000000
危险品标志：Xi

用途
抗风湿与镇痛药,用于治疗风湿、高血压、肺癌等病症