Podophyllotoxin (abbreviated as PPT), otherwise known as podofilox, is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species. Under the trade names Condylox, a gel, and Wartec, a solution or cream, it is used on the skin as a topical treatment of external genital warts, caused by some types of the human papillomavirus (HPV), and other warts. PPT and its synthetic derivatives display a wide selection in medical applications such as purgative, vesicant, antirheumatic, antiviral, and antitumor agents. These derivatives include etoposide and teniposide. Their anticancer activity has been heavily under study and used in various chemotherapies, including lung cancer, lymphomas, and genital tumors.

CAS：518-28-5
中文别名：鬼臼脂毒;
英文别名：Furo[3‘,4‘:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5-,5aα,8a-,9-)]-;Podophyllotoxin;(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one;
分子式：C22H22O8
分子量：414.405
精确质量：414.131
Psa：92.68
Logp：2.4092

MDL号：MFCD00075290

外观与性状：淡黄色-米色粉末
密度：1.37g/cm3
沸点：597.9ºC at 760 mmHg
熔点：183-184°C(lit.)
闪点：210.2ºC
稳定性：Stable under normal temperatures and pressures.
储存条件：2-8ºC

RTECS号：LV2500000
安全说明：S36/37/39-S45
危险类别码：R23/25
WGK Germany：3
危险品运输编码：UN 3462 6.1/PG 2
海关编码：2942000000
危险类别：6.1(a)
包装等级：II
危险品标志：T
危险性防范说明：P261; P280; P302 + P350; P305 + P351 + P338; P310
危险性描述：H301; H310; H315; H319; H335
危险标志：GHS06
信号词：Danger

生产方法
从小檗科植物中华山荷叶(Diphylleia sinensishi Li)的根茎中提取。 主要用于尖锐湿疣,也可用于其他病毒疣。
用途
主要用于尖锐湿疣,也可用于其他病毒疣。