Demecolceine (7S)-10-hydroxy-1,2,3-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one CAS号518-11-6分子式、结构式、MSDS、物化性质、用途-化学科研者一站式服务平台

化合物简介

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

基本信息

CAS：518-11-6
中文别名：
英文别名：Demecolcein;(S)-10-hydroxy-1,2,3-trimethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-one;demecolceine;(S)-10-Hydroxy-1,2,3-trimethoxy-7-methylamino-6,7-dihydro-5H-benzo[a]heptalen-9-on;N-Desacetyl-N-methylcolchiceine;(7s)-9-hydroxy-1,2,3-trimethoxy-7-(methylamino)-6,7-dihydrobenzo[a]heptalen-10(5h)-one;
分子式：C20H23NO5
分子量：357.4
精确质量：357.158
Psa：77.02
Logp：3.0428