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  • 双(叔丁氧羰基)胺

    Di-tert-butyl iminodicarboxylate

化合物简介

Di-tert-butyl-iminodicarboxylate is an organic compound that can be described with the formula [(CH3)3COC(O)]2NH. It is a white solid that is soluble in organic solvents. The compound is used as a reagent for the preparation of primary amines from alkyl halides. It was popularized as an alternative to the Gabriel synthesis for the same conversion. Amines can also be prepared from alcohols by dehydration using the Mitsunobu reaction.

基本信息

CAS:51779-32-9
中文别名:亚氨二甲酸二叔丁酯;N-Boc-氨基甲酸叔丁酯;亚胺二羧酸二叔丁酯;二叔丁基亚氨草酸;
英文别名:Iminodicarboxylic Acid Di-tert-butyl Ester;N-Boc-tert-butylcarbamate;tert-butyl N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate;tert-Butyl iminodicarboxylate;
分子式:C10H19NO4
分子量:217.262
精确质量:217.131
Psa:64.63
Logp:2.8371

编号系统

MDL号:MFCD00043309

物化性质

外观与性状:白色至淡的黄色粉末
密度:1.037 g/cm3
沸点:273.8ºC at 760 mmHg
熔点:114-117°C(lit.)
闪点:119.4ºC
折射率:1.442
储存条件:2-8ºC

安全信息

安全说明:S26-S37/39
危险类别码:R36/37/38
WGK Germany:3
海关编码:2925290090
危险品标志:Xi

生产方法及用途

合成路线

  • 参考文献

    Bunnenberg, Rolf; Jochims, Johannes C. Chemische Berichte, 1981 , vol. 114, # 6 p. 2064 - 2074

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图谱

13C NMR : Predict


1H NMR : Predict


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