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化合物简介
Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with Fusarium graminearum (Gibberella zeae) and F. culmorum, both of which are important plant pathogens which cause fusarium head blight in wheat and gibberella or fusarium ear blight in maize. A direct relationship between the incidence of fusarium head blight and contamination of wheat with deoxynivalenol has been established. The incidence of fusarium head blight is strongly associated with moisture at the time of flowering (anthesis), and the timing of rainfall, rather than the amount, is the most critical factor. However, increased amount of moisture towards harvest time has been associated with lower amount of vomitoxin in wheat grain due to leaching of toxins. Furthermore, deoxynivalenol contents are significantly affected by the susceptibility of cultivars towards Fusarium species, previous crop, tillage practices, and fungicide use. It occurs abundantly in grains in Norway due to heavy rainfall.
基本信息
CAS:51481-10-8
中文别名:脱氧雪腐镰刀菌烯醇;3Α,7Α,15-三羟基-12,13-环氧单端孢霉-9-蒽-8-酮;呕吐毒素;3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one;别名:呕吐毒素;
英文别名:(3beta,7alpha,12R)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one;DEOXYNIVALENOL;
分子式:C15H20O6
分子量:296.316
精确质量:296.126
Psa:99.52
Logp:-0.8377
中文别名:脱氧雪腐镰刀菌烯醇;3Α,7Α,15-三羟基-12,13-环氧单端孢霉-9-蒽-8-酮;呕吐毒素;3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one;别名:呕吐毒素;
英文别名:(3beta,7alpha,12R)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one;DEOXYNIVALENOL;
分子式:C15H20O6
分子量:296.316
精确质量:296.126
Psa:99.52
Logp:-0.8377
编号系统
UNII:JT37HYP23V
物化性质
密度:1.48g/cm3
沸点:543.9ºC at 760mmHg
熔点:151-153ºC
闪点:206.9ºC
折射率:1.632
稳定性:Stable. Incompatible with strong oxidizing agents.
储存条件:库房低温,通风,干燥,与食品原料分开存放
沸点:543.9ºC at 760mmHg
熔点:151-153ºC
闪点:206.9ºC
折射率:1.632
稳定性:Stable. Incompatible with strong oxidizing agents.
储存条件:库房低温,通风,干燥,与食品原料分开存放
安全信息
危险类别码:R25; R68/20/21/22; R67; R66; R36; R20/21/22; R11; R36/37/38
危险品运输编码:UN 2811 6.1/PG 2
危险类别:6.1(a)
危险品标志:T; Xn; F; Xi
危险性防范说明:P264; P301 + P310
危险标志:GHS06
信号词:Danger
危险性描述:H300
危险品运输编码:UN 2811 6.1/PG 2
危险类别:6.1(a)
危险品标志:T; Xn; F; Xi
危险性防范说明:P264; P301 + P310
危险标志:GHS06
信号词:Danger
危险性描述:H300
生产方法及用途
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
