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化合物简介
Withaferin A is a steroidal lactone, derived from Acnistus arborescens, Withania somnifera (Indian Winter cherry or Ashwagandha in Sanskrit) and other members of Solanaceae family. It has been traditionally used in the ayurvedic medicine. It is the first member of the withanolide class of ergostane type product to be discovered. This natural product has wide range of pharmacological activities including cardioprotective, anti-inflammatory, immuno-modulatory, anti-angiogenesis, anti-metastasis and anti-carcinogenic properties.
基本信息
CAS:5119-48-2
中文别名:醉茄素A;
英文别名:Withaferin A;5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide,Withaferine A;
分子式:C28H38O6
分子量:470.598
精确质量:470.267
Psa:96.36
Logp:3.3529
中文别名:醉茄素A;
英文别名:Withaferin A;5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide,Withaferine A;
分子式:C28H38O6
分子量:470.598
精确质量:470.267
Psa:96.36
Logp:3.3529
编号系统
UNII:L6DO3QW4K5
物化性质
密度:1.28g/cm3
沸点:680.7ºC at 760 mmHg
熔点:252-253ºC
闪点:226.7ºC
折射率:1.599
储存条件:Desiccate at -20ºC
沸点:680.7ºC at 760 mmHg
熔点:252-253ºC
闪点:226.7ºC
折射率:1.599
储存条件:Desiccate at -20ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR
