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化合物简介

Withaferin A is a steroidal lactone, derived from Acnistus arborescens, Withania somnifera (Indian Winter cherry or Ashwagandha in Sanskrit) and other members of Solanaceae family. It has been traditionally used in the ayurvedic medicine. It is the first member of the withanolide class of ergostane type product to be discovered. This natural product has wide range of pharmacological activities including cardioprotective, anti-inflammatory, immuno-modulatory, anti-angiogenesis, anti-metastasis and anti-carcinogenic properties.

基本信息

CAS:5119-48-2
中文别名:醉茄素A;
英文别名:Withaferin A;5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide,Withaferine A;
分子式:C28H38O6
分子量:470.598
精确质量:470.267
Psa:96.36
Logp:3.3529

编号系统

UNII:L6DO3QW4K5

物化性质

密度:1.28g/cm3
沸点:680.7ºC at 760 mmHg
熔点:252-253ºC
闪点:226.7ºC
折射率:1.599
储存条件:Desiccate at -20ºC

安全信息

生产方法及用途

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图谱

Predict 1H proton NMR


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