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化合物简介

Trimetazidine is a drug for angina pectoris sold under the brand name Vastarel MR. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of fatty acid metabolism, also known as fatty acid oxidation inhibitor.

基本信息

CAS:5011-34-7
中文别名:1-(2,3,4-三甲氧基苄基)哌嗪;
英文别名:1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;Vastarel;1-(2,3,4-trimethoxybenzyl)piperazine;
分子式:C14H22N2O3
分子量:266.336
精确质量:266.163
Psa:42.96
Logp:1.3843

编号系统

MDL号:MFCD00243086

物化性质

外观与性状:白色或灰白色结晶粉末
密度:1.092 g/cm3
沸点:364ºC at 760 mmHg
熔点:200 - 205ºC
闪点:174ºC
储存条件:Store in original container in a cool dark place.

安全信息

海关编码:2933599090
危险品标志:Xi

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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