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化合物简介

Butein is a chalconoid. It can be found in Toxicodendron vernicifluum (or formerly Rhus verniciflua), Dahlia, Butea (Butea monosperma) and Coreopsis It has antioxidative, aldose reductase and advanced glycation endproducts inhibitory effects. It is also a sirtuin-activating compound, a chemical compound having an effect on sirtuins, a group of enzymes that use NAD+ to remove acetyl groups from proteins. It turned out that buteins possess a high ability to inhibit aromatase process in the human body, for this reason, the use of these compounds in the treatment of breast cancer on the estrogen ground has been taken into account. The first attempts of sport pro-hormone supplementation with the use of buteins took place in Poland.

基本信息

CAS:487-52-5
中文别名:紫铆查尔酮;反式-2\',3,4,4\'-四羟基查尔酮;
英文别名:(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one;(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one;(E)-2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-;2\',3,4,4\'-TETRAHYDROCHALCONE;2\',3,4,4\'-TETRAHYDROXYCHALCONE;2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)- (2E)-;3,4,2\',4\'-TETRAHYDROXYCHALCONE;Chalcone, 2\',3,4,4\'-tetrahydroxy-;Einecs 207-659-5;
分子式:C15H12O5
分子量:272.253
精确质量:272.068
Psa:97.99
Logp:2.4051

编号系统

EINECS号:207-659-5

物化性质

密度:1.483g/cm3
沸点:560.9ºC at 760mmHg
熔点:216°C
闪点:307.1ºC
折射率:1.748
储存条件:-20ºC
蒸汽压:3.46E-13mmHg at 25°C

安全信息

安全说明:S22-S24/25
WGK Germany:3

生产方法及用途

合成路线

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图谱

13C NMR : Predict


1H NMR : Predict


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