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  • 3-羟基苯并(a)蒽

    benzo[a]anthracen-3-ol

化合物简介

Benz[a]anthracen-3-ol is a derivative of the most potent carcinogenic hydrocarbon, 7,12-Dimethylbenz[a]anthracene, a highly potent carcinogen that is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading ultimately to tumor induction. Benz[a]anthracen-3-ol is used in carcinogenesis studies relating to breast cancer.

基本信息

CAS:4834-35-9
中文别名
英文别名:3-Hydroxybenzanthracene;3-OH-Baa;tetraphen-3-ol;
分子式:C18H12O
分子量:244.287
精确质量:244.089
Psa:20.23
Logp:4.8518

编号系统

物化性质

密度:1.284g/cm3
沸点:498.2ºC at 760 mmHg
闪点:240.4ºC
折射率:1.804

安全信息

生产方法及用途

合成路线

  • 参考文献

    Harvey; Cortez; Sugiyama; Ito; Sawyer; DiGiovanni Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 154 - 159

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图谱

1H NMR : Predict


13C NMR : Predict


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