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  • 芦荟大黄素

    Aloe emodin

化合物简介

Aloe emodin is an anthraquinone present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe emodin is found in the gel, sap or leaves of Aloe vera ,the bark of Frangula (Rhamnus frangula) and Cascara Sagrada (Rhamnus purshiana), the leaves of Senna (Cassia angustifolia), and the rhizome of Rhubarb (Rheum rhaponticum). It has a marked anti-viral effect in vitro against both herpes simplex virus (HSV) type 1 and 2.

基本信息

CAS:481-72-1
中文别名:1,8-二羟基-3-(羟基甲基)蒽醌;1.8-二羟基-3-羟甲基蒽醌;1,8-二羟基-3-羟甲基蒽醌;芦荟泻素;
英文别名:Rhabarberone;3-Hydroxymethylchrysazin;1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone,3-Hydroxymethylchrysazine;1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone;Aloe Emodin;Diacerein impurity B;Aloeemodin;1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone,3-Hydroxymethylchrysazine,Aloe-emodin;9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-;Aloe-emodin;3-Hydroxymethylchrysazine;EMODINE;
分子式:C15H10O5
分子量:270.237
精确质量:270.053
Psa:94.83
Logp:1.3655

编号系统

UNII:C8IYT9CR7C

物化性质

外观与性状:橙色针状结晶(由甲苯中)。易溶于热乙醇,在苯及乙醚中呈黄色,在氨水和硫酸中呈绯红色,属蒽醌类化合物,在酸性溶液中被还原则生成蒽酚及其互变异构体的蒽酮。熔点:223~224℃
熔点:223-224°C
储存条件:2-8°C

安全信息

RTECS号:CB6712200
安全说明:S26; S36
WGK Germany:3
危险类别码:R36/37/38
危险品标志:Xi

生产方法及用途

用途
具有抗菌作用,对葡萄球菌、链球菌、白喉、枯草、痢疾等杆菌均有抑制作用。还有泻下作用,临床作为泻药。

合成路线

上游原料

下游产品

图谱

1H NMR : Predict


13C NMR : Predict


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