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化合物简介
Epiandrosterone, or 3β-androsterone, also known as 3β-hydroxy-5α-androstan-17-one or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity. It is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductase enzyme. It was first isolated in 1931, by Adolf Friedrich Johann Butenandt and Kurt Tscherning. They distilled over 17,000 litres of male urine, from which they got 50 milligrams of crystalline androsterone (most likely mixed isomers), which was sufficient to find that the chemical formula was very similar to estrone.
基本信息
CAS:481-29-8
中文别名:表雄甾酮;5α-雄甾-3β-醇-17-酮;异雄甾酮;异雄酮,异雄酮;METHYL MASTERDROL;
英文别名:3BETA-HYDROXY-5ALPHA-ANDROSTAN-17-ONE;ISOANDROSTERONE;D-epiandrosterone;3b-Androsterone;TRANS-ANDROSTERONE;Androstan-17-one, 3-hydroxy-, (3β,5α)-;trans-Androsterone;3beta-Androsterone;epiandrosteron;EPLANDROSTERONE;Epiandrosterone;
分子式:C19H30O2
分子量:290.44
精确质量:290.225
Psa:37.3
Logp:3.9591
中文别名:表雄甾酮;5α-雄甾-3β-醇-17-酮;异雄甾酮;异雄酮,异雄酮;METHYL MASTERDROL;
英文别名:3BETA-HYDROXY-5ALPHA-ANDROSTAN-17-ONE;ISOANDROSTERONE;D-epiandrosterone;3b-Androsterone;TRANS-ANDROSTERONE;Androstan-17-one, 3-hydroxy-, (3β,5α)-;trans-Androsterone;3beta-Androsterone;epiandrosteron;EPLANDROSTERONE;Epiandrosterone;
分子式:C19H30O2
分子量:290.44
精确质量:290.225
Psa:37.3
Logp:3.9591
编号系统
UNII:8TR252Z538
物化性质
外观与性状:白色至灰白色结晶粉末
密度:1.085 g/cm3
沸点:413.1ºC at 760 mmHg
熔点:172-174°C
闪点:176.4ºC
折射率:1.536
水溶解性:practically insoluble
稳定性:Stable under normal temperatures and pressures.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
蒸汽压:0mmHg at 25°C
密度:1.085 g/cm3
沸点:413.1ºC at 760 mmHg
熔点:172-174°C
闪点:176.4ºC
折射率:1.536
水溶解性:practically insoluble
稳定性:Stable under normal temperatures and pressures.
储存条件:Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
蒸汽压:0mmHg at 25°C
安全信息
安全说明:S22-S24/25
WGK Germany:3
海关编码:2937290090
WGK Germany:3
海关编码:2937290090
生产方法及用途
生产方法
用5-雄甾烯-3β-醇-17-酮3-醋酸酯以钯炭催化氢化,得雄甾烷-3β-醇-17酮3-醋酸酯,然后以氢氧化钠溶液水解,制得该品。 生产甾体激素类药物。
用途
生产甾体激素类药物。
用5-雄甾烯-3β-醇-17-酮3-醋酸酯以钯炭催化氢化,得雄甾烷-3β-醇-17酮3-醋酸酯,然后以氢氧化钠溶液水解,制得该品。 生产甾体激素类药物。
用途
生产甾体激素类药物。
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

13C NMR : in CDCl3

Mass

IR : KBr disc

IR : nujol mull
