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化合物简介

Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade. It induces sedation, hypothermia, ptosis, and (in higher doses) catalepsy; it inhibits spontaneous motor activity, conditioned avoidance response, amphetamine toxicity and stereotypy. Nuciferine may also potentiate morphine analgesia. The median lethal dose in mice is 289mg/kg. It is structurally related to apomorphine.

基本信息

CAS:475-83-2
中文别名:荷叶碱NUCIFERIN;荷叶碱;
英文别名:Sanjoinine E;l-nuciferine;nuciferin;l-5,6-dimethoxyaporphine;Nuciferin;R-(-)-nuciferine;
分子式:C19H21NO2
分子量:295.376
精确质量:295.157
Psa:21.7
Logp:3.3938

编号系统

UNII:W26UEB90B7

物化性质

密度:1.15g/cm3
沸点:430.7ºC at 760mmHg
闪点:151.9ºC
折射率:1.596
蒸汽压:1.27E-07mmHg at 25°C

安全信息

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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