化学科研者一站式服务平台


  • 维洛沙秦

    2-[(2-ethoxyphenoxy)methyl]morpholine

化合物简介

Viloxazine (Vivalan, Emovit, Vivarint, Vicilan) is a morpholine derivative and is a selective norepinephrine reuptake inhibitor (NRI). It was used as an antidepressant in some European countries, and produced a stimulant effect that is similar to the amphetamines, except without any signs of dependence. It was discovered and brought to market in 1976 by Imperial Chemical Industries and was withdrawn from the market in the early 2000s for business reasons.

基本信息

CAS:46817-91-8
中文别名:2-((2-乙氧基苯氧基)甲基)吗啉;
英文别名:Emovit;Morpholine,2-((2-ethoxyphenoxy)methyl);Viloxazinum [INN-Latin];2-(2-Ethoxy-phenoxymethyl)-morpholine;2-(o-ethoxyphenoxymethyl)morpholine;viloxazine;Viloxazin;Viloxazina [INN-Spanish];
分子式:C13H19NO3
分子量:237.295
精确质量:237.136
Psa:39.72
Logp:1.7813

编号系统

UNII:5I5Y2789ZF

物化性质

密度:1.061 g/cm3
沸点:350.5ºC at 760 mmHg
熔点:185-186ºC
闪点:144.3ºC
折射率:1.499

安全信息

生产方法及用途

合成路线

  • 参考文献

    Audouze, Karine; Nielsen, Elsebet stergaard.; Peters, Dan Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3089 - 3104

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


加载中...