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化合物简介

Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone, a painkiller roughly half again more or up to 1.7× the strength of morphine. The latter can also be synthesized from thebaine, however.

基本信息

CAS:467-13-0
中文别名
英文别名:6-Oxocodeine;dihydrocodeine;hydrocodone;6-Codeinone;(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;EINECS 207-386-1;
分子式:C18H19NO3
分子量:297.348
精确质量:297.136
Psa:38.77
Logp:1.6472

编号系统

UNII:22B5AW0ANN

物化性质

密度:1.34 g/cm3
沸点:466.9ºC at 760 mmHg
熔点:182-183ºC
闪点:236.1ºC
折射率:1.656
储存条件:Controlled Substance, -20ºC Freezer
蒸汽压:6.84E-09mmHg at 25°C

安全信息

危险类别码:R22

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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