化学科研者一站式服务平台
化合物简介
Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone, a painkiller roughly half again more or up to 1.7× the strength of morphine. The latter can also be synthesized from thebaine, however.
基本信息
CAS:467-13-0
中文别名:
英文别名:6-Oxocodeine;dihydrocodeine;hydrocodone;6-Codeinone;(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;EINECS 207-386-1;
分子式:C18H19NO3
分子量:297.348
精确质量:297.136
Psa:38.77
Logp:1.6472
中文别名:
英文别名:6-Oxocodeine;dihydrocodeine;hydrocodone;6-Codeinone;(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;EINECS 207-386-1;
分子式:C18H19NO3
分子量:297.348
精确质量:297.136
Psa:38.77
Logp:1.6472
编号系统
UNII:22B5AW0ANN
物化性质
密度:1.34 g/cm3
沸点:466.9ºC at 760 mmHg
熔点:182-183ºC
闪点:236.1ºC
折射率:1.656
储存条件:Controlled Substance, -20ºC Freezer
蒸汽压:6.84E-09mmHg at 25°C
沸点:466.9ºC at 760 mmHg
熔点:182-183ºC
闪点:236.1ºC
折射率:1.656
储存条件:Controlled Substance, -20ºC Freezer
蒸汽压:6.84E-09mmHg at 25°C
安全信息
危险类别码:R22
生产方法及用途
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
