Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. The drug was developed by AstraZeneca.

CAS：443913-73-3
中文别名：4-(4-溴-2-氟苯胺基)-6-甲氧基-7-[(1-甲基哌啶-4-基)甲氧基]喹唑啉;ZD6474;ZACTIMA;
英文别名：Zactima;Vandetanib;Vandetanib for research;ZD 6474;N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine;
分子式：C22H24BrFN4O2
分子量：475.354
精确质量：474.107
Psa：59.51
Logp：5.0151

MDL号：MFCD07772346

外观与性状：白色固体
密度：1.406
沸点：538.2ºC at 760 mmHg
熔点：240-243ºC
闪点：279.3ºC

海关编码：2933990090

用途
抗肿瘤原料。