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化合物简介

Harmine, also known as telepathine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as \"yage\" or \"ayahuasca\"). Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a RIMA. Harmine selectively binds to MAO-A but does not inhibit the variant MAO-B.

基本信息

CAS:442-51-3
中文别名:7-甲氧基-1-甲基-9H-吡啶并[3,4-b]吲哚;哈尔碱;去氢骆驼蓬碱;哈尔明碱;骆驼蓬碱;
英文别名:Yageine;9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-;Harmin;Yajeine;Banisterine;7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole;Harmine;Telepathin;BANISTERINE MONOHYDRATE;Yagein;Garmin;Telepathien;
分子式:C13H12N2O
分子量:212.247
精确质量:212.095
Psa:37.91
Logp:3.0331

编号系统

MDL号:MFCD00004958

物化性质

外观与性状:灰白色固体
密度:1.252g/cm3
沸点:421.4ºC at 760mmHg
熔点:262-264°C(lit.)
闪点:139.7ºC
折射率:1.706
储存条件:库房低温,通风,干燥,与食品原料分开存放
蒸汽压:6.42E-07mmHg at 25°C

安全信息

RTECS号:UV0175000
安全说明:S22; S24/25; S36/37; S26; S36
WGK Germany:3
危险类别码:R20/21/22; R36
危险品运输编码:1544
海关编码:2933990090
危险类别:6.1
包装等级:III
危险品标志:Xn

生产方法及用途

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


IR : KBr disc


IR : nujol mull


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