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化合物简介
Acivicin is an inhibitor of gamma-glutamyl transferase. It is fermented product of Streptomyces sviceus and has promise as an antineoplastic agent. It interferes with glutamate metabolism and inhibits glutamate dependent synthesis of enzymes, and is thereby potentially helpful in treatment of solid tumors.
基本信息
CAS:42228-92-2
中文别名:异恶唑醋酸;
英文别名:ACIA;Antibiotic AT 125;Acivicinum;Acivicino;(2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid;Acivicine;AT-125;
分子式:C5H7ClN2O3
分子量:178.574
精确质量:178.015
Psa:84.91
Logp:-0.1246
中文别名:异恶唑醋酸;
英文别名:ACIA;Antibiotic AT 125;Acivicinum;Acivicino;(2S)-2-amino-2-[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid;Acivicine;AT-125;
分子式:C5H7ClN2O3
分子量:178.574
精确质量:178.015
Psa:84.91
Logp:-0.1246
编号系统
UNII:O0X60K76I6
物化性质
密度:1.85g/cm3
沸点:341.6ºC at 760 mmHg
熔点:>200ºC (dec.)
闪点:160.4ºC
折射率:1.663
储存条件:2-8ºC
沸点:341.6ºC at 760 mmHg
熔点:>200ºC (dec.)
闪点:160.4ºC
折射率:1.663
储存条件:2-8ºC
安全信息
安全说明:S36
危险类别码:R20/21/22
危险品运输编码:UN 3172
危险类别:6.1(b)
包装等级:III
危险品标志:Xn
危险类别码:R20/21/22
危险品运输编码:UN 3172
危险类别:6.1(b)
包装等级:III
危险品标志:Xn
生产方法及用途
合成路线
上游原料
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图谱
13C NMR : Predict

1H NMR : Predict
