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化合物简介
SB-649,915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist which is being investigated for its antidepressant effects. Relative to the selective serotonin reuptake inhibitors (SSRIs), SB-649,915 has a faster onset of action and may also have greater clinical efficacy as well. This can be attributed to blockade of 5-HT1A and 5-HT1B autoreceptors which inhibit serotonin release.
基本信息
CAS:420785-70-2
中文别名:
英文别名:6-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-methyl]-2,3-dimethoxy-benzoic acid ethyl ester;ETHYL 6-[(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)IMINOMETHYL]-2,3-DIMETHOXY-BENZOATE;Benzoic acid,6-(((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)imino)methyl)-2,3-dimethoxy-,ethyl ester;6-[(1-{2-[(2-methyl-5-quinolinyl)oxy]ethyl}-4-piperidinyl)methyl]-2H-1,4-benzoxazin-3(4H)-one;
分子式:C26H29N3O3
分子量:431.527
精确质量:431.221
Psa:67.18
Logp:4.2306
中文别名:
英文别名:6-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)-methyl]-2,3-dimethoxy-benzoic acid ethyl ester;ETHYL 6-[(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)IMINOMETHYL]-2,3-DIMETHOXY-BENZOATE;Benzoic acid,6-(((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)imino)methyl)-2,3-dimethoxy-,ethyl ester;6-[(1-{2-[(2-methyl-5-quinolinyl)oxy]ethyl}-4-piperidinyl)methyl]-2H-1,4-benzoxazin-3(4H)-one;
分子式:C26H29N3O3
分子量:431.527
精确质量:431.221
Psa:67.18
Logp:4.2306
编号系统
物化性质
安全信息
生产方法及用途
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上游原料
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图谱
1H NMR : Predict

13C NMR : Predict
