Escaline or 3,5-methoxy-4-ethoxyphenethylamine is a psychedelic drug and entheogen of the phenethylamine class of compounds. Escaline was first synthesized and reported in the scientific literature by Benington, et al., in 1954, but was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues that included escaline, proscaline, and isoproscaline. The effects of this and related mescaline analogues in humans were first described by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 40 to 60mg, consumed orally. The duration of action was stated to be 8 – 12 hours.

CAS：39201-82-6
中文别名：
英文别名：3,5-Dimethoxy-4 ethoxyphenylethylamine;4-ethoxy-3,5-dimethoxy-phenethylamine;4-Aethoxy-3,5-dimethoxy-phenaethylamine;
分子式：C12H19NO3
分子量：225.284
精确质量：225.136
Psa：53.71
Logp：2.304

密度：1.05g/cm3
沸点：327.6ºC at 760 mmHg
闪点：153.4ºC
折射率：1.508