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化合物简介
Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substance G. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone.
基本信息
CAS:382-45-6
中文别名:雄甾-4-烯-3,11,17-三酮;4-雄烯-3,11,17-三酮;ADRENOSTERONE (11-OXO);
英文别名:Reichstein’s substance G;androst-4-ene-3,11,17-trione;Androst-4-ene-3,11,17-trione;11-KETOANDROSTENEDIONE;4-androsten-11-keto-3,17-dione;Reichstein\'s Substance G;Andrenosterone;11-Ketoandrostenedione;Androsten-(4)-trion-(3.11.17);Androst-4-en-3,11,17-trion;REICHSTEIN\'S \'G\';4-androsten-11,3,17-trione;11-Oxy-4-androstenedione;4-androstene-3,11,17-trione;4-ANDROSTEN-3,11,17-TRIONE;REICHSTEIN\'S SUBSTANCE G;4-Androstene-3,11,17-trione;
分子式:C19H24O3
分子量:300.392
精确质量:300.173
Psa:51.21
Logp:3.2664
中文别名:雄甾-4-烯-3,11,17-三酮;4-雄烯-3,11,17-三酮;ADRENOSTERONE (11-OXO);
英文别名:Reichstein’s substance G;androst-4-ene-3,11,17-trione;Androst-4-ene-3,11,17-trione;11-KETOANDROSTENEDIONE;4-androsten-11-keto-3,17-dione;Reichstein\'s Substance G;Andrenosterone;11-Ketoandrostenedione;Androsten-(4)-trion-(3.11.17);Androst-4-en-3,11,17-trion;REICHSTEIN\'S \'G\';4-androsten-11,3,17-trione;11-Oxy-4-androstenedione;4-androstene-3,11,17-trione;4-ANDROSTEN-3,11,17-TRIONE;REICHSTEIN\'S SUBSTANCE G;4-Androstene-3,11,17-trione;
分子式:C19H24O3
分子量:300.392
精确质量:300.173
Psa:51.21
Logp:3.2664
编号系统
MDL号:MFCD00003606
物化性质
外观与性状:灰白色至淡黄色固体
密度:1.18g/cm3
沸点:476.1ºC at 760mmHg
熔点:219-222°C(lit.)
闪点:206ºC
折射率:290 ° (C=0.2, EtOH)
密度:1.18g/cm3
沸点:476.1ºC at 760mmHg
熔点:219-222°C(lit.)
闪点:206ºC
折射率:290 ° (C=0.2, EtOH)
安全信息
WGK Germany:3
海关编码:2942000000
海关编码:2942000000
生产方法及用途
用途
优质医药原料。
优质医药原料。
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
