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  • 肾上腺甾酮

    Adrenosterone

化合物简介

Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substance G. Adrenosterone occurs in trace amounts in humans as well as most mammals and in larger amounts in fish, where it is a precursor to the primary androgen, 11-ketotestosterone.

基本信息

CAS:382-45-6
中文别名:雄甾-4-烯-3,11,17-三酮;4-雄烯-3,11,17-三酮;ADRENOSTERONE (11-OXO);
英文别名:Reichstein’s substance G;androst-4-ene-3,11,17-trione;Androst-4-ene-3,11,17-trione;11-KETOANDROSTENEDIONE;4-androsten-11-keto-3,17-dione;Reichstein\'s Substance G;Andrenosterone;11-Ketoandrostenedione;Androsten-(4)-trion-(3.11.17);Androst-4-en-3,11,17-trion;REICHSTEIN\'S \'G\';4-androsten-11,3,17-trione;11-Oxy-4-androstenedione;4-androstene-3,11,17-trione;4-ANDROSTEN-3,11,17-TRIONE;REICHSTEIN\'S SUBSTANCE G;4-Androstene-3,11,17-trione;
分子式:C19H24O3
分子量:300.392
精确质量:300.173
Psa:51.21
Logp:3.2664

编号系统

MDL号:MFCD00003606

物化性质

外观与性状:灰白色至淡黄色固体
密度:1.18g/cm3
沸点:476.1ºC at 760mmHg
熔点:219-222°C(lit.)
闪点:206ºC
折射率:290 ° (C=0.2, EtOH)

安全信息

WGK Germany:3
海关编码:2942000000

生产方法及用途

用途
优质医药原料。

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


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