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化合物简介
2-Fluoroethanol is the chemical compound with the formula CH2FCH2OH and the simplest fluorohydrin. This colorless liquid is one of the simplest stable fluorinated alcohols. It was developed for use as a rodenticide, insecticide, and acaricide. Owing to its easy oxidation to fluoroacetic acid, fluoroethanol is highly toxic (LD50 = 10 mg/kg). The related difluoro- and trifluoroethanols are far less dangerous.
基本信息
CAS:371-62-0
中文别名:2-氟代乙醇;氟乙醇;
英文别名:2-Fluoroethan-1-ol;2-fluoro-ethano;Ethanol, 2-fluoro-;2-fluoroethyl alcohol;2-fluroethanol;FLUOROETHANOL;Glycolfluorohydrin;MONOFLUOROETHANOL;2-monofluoroethanol;2-fluoro-1-ethanol;CH2FCH2OH;2-fluoro-ethanol;TL 741;
分子式:C2H5FO
分子量:64.0589
精确质量:64.0324
Psa:20.23
Logp:-0.0518
中文别名:2-氟代乙醇;氟乙醇;
英文别名:2-Fluoroethan-1-ol;2-fluoro-ethano;Ethanol, 2-fluoro-;2-fluoroethyl alcohol;2-fluroethanol;FLUOROETHANOL;Glycolfluorohydrin;MONOFLUOROETHANOL;2-monofluoroethanol;2-fluoro-1-ethanol;CH2FCH2OH;2-fluoro-ethanol;TL 741;
分子式:C2H5FO
分子量:64.0589
精确质量:64.0324
Psa:20.23
Logp:-0.0518
编号系统
MDL号:MFCD00002828
物化性质
外观与性状:无色液体
密度:1.091g/mLat 25°C(lit.)
沸点:103°C757mm Hg(lit.)
熔点:−26.5°C(lit.)
闪点:88°F
折射率:n20/D 1.365(lit.)
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:16 mm Hg ( 20 °C)
密度:1.091g/mLat 25°C(lit.)
沸点:103°C757mm Hg(lit.)
熔点:−26.5°C(lit.)
闪点:88°F
折射率:n20/D 1.365(lit.)
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:16 mm Hg ( 20 °C)
安全信息
RTECS号:KL1575000
安全说明:S36/37/39-S45
WGK Germany:3
危险类别码:R10; R26/27/28
危险品运输编码:UN 3383 6.1/PG 1
海关编码:2905590090
危险类别:6.1
包装等级:I
危险品标志:T+; F
安全说明:S36/37/39-S45
WGK Germany:3
危险类别码:R10; R26/27/28
危险品运输编码:UN 3383 6.1/PG 1
海关编码:2905590090
危险类别:6.1
包装等级:I
危险品标志:T+; F
生产方法及用途
生产方法
将2-氯乙醇96.6g(1.2mol)滴加到94ml乙二醇和105g(1.8mol)无水氟化钾的混合物中,在180℃保温反应2h,得2-氟乙醇32.34g,收率42.1%。 用作医药、农药中间体。
用途
用作医药、农药中间体。
将2-氯乙醇96.6g(1.2mol)滴加到94ml乙二醇和105g(1.8mol)无水氟化钾的混合物中,在180℃保温反应2h,得2-氟乙醇32.34g,收率42.1%。 用作医药、农药中间体。
用途
用作医药、农药中间体。
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

Mass spectrum (electron ionization)
