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化合物简介
5-HO-DiPT (5-hydroxy-N,N-di-iso-propyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high 5-HT2A affinity and good selectivity over 5-HT1A, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces mainly peripheral effects.
基本信息
CAS：36288-76-3
中文别名：
英文别名：1H-Indol-5-ol,3-[2-[bis(1-methylethyl)amino]ethyl];3-(2-Diisopropylamino-aethyl)-indol-5-ol;3-(2-diisopropylamino-ethyl)-indol-5-ol;5-Hydroxy-N,N-diisopropyltryptamine;3-(2-(DIISOPROPYLAMINO)ETHYL)-1H-INDOL-5-OL;
分子式：C16H24N2O
分子量：260.375
精确质量：260.189
Psa：39.26
Logp：3.5348
中文别名：
英文别名：1H-Indol-5-ol,3-[2-[bis(1-methylethyl)amino]ethyl];3-(2-Diisopropylamino-aethyl)-indol-5-ol;3-(2-diisopropylamino-ethyl)-indol-5-ol;5-Hydroxy-N,N-diisopropyltryptamine;3-(2-(DIISOPROPYLAMINO)ETHYL)-1H-INDOL-5-OL;
分子式：C16H24N2O
分子量：260.375
精确质量：260.189
Psa：39.26
Logp：3.5348
编号系统
物化性质
安全信息
生产方法及用途
合成路线
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参考文献
Narimatsu, Shizuo; Yonemoto, Rei; Saito, Keita; Takaya, Kazuo; Kumamoto, Takuya; Ishikawa, Tsutomu; Asanuma, Masato; Funada, Masahiko; Kiryu, Kimio; Naito, Shinsaku; Yoshida, Yuzo; Yamamoto, Shigeo; Hanioka, Nobumitsu Biochemical Pharmacology, 2006 , vol. 71, # 9 p. 1377 - 1385
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
