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  • A1受体拮抗剂,CPT

    8-cyclopentyl-1,3-dimethyl-7H-purine-2,6-dione

化合物简介

8-Cyclopentyl-1,3-dimethylxanthine (8-Cyclopentyltheophylline, 8-CPT, CPX) is a drug which acts as a potent and selective antagonist for the adenosine receptors, with some selectivity for the A1 receptor subtype, as well as a non-selective phosphodiesterase inhibitor. It has stimulant effects in animals with slightly higher potency than caffeine.

基本信息

CAS:35873-49-5
中文别名:8-环戊-1,3-二甲基黄嘌呤;
英文别名:8-Cyclopentyltheophylline CPT;8-Cyclopentyl-1,3-dimethylxanthine;8-Cyclopentyl theophylline;Theophylline,8-cyclopentyl;cyclopentyl teophylline;1,3-dimethyl-8-cyclopentylxanthine;Xanthine,8-cyclopentyl-1,3-dimethyl;8-cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione;
分子式:C12H16N4O2
分子量:248.281
精确质量:248.127
Psa:72.68
Logp:0.6179

编号系统

物化性质

密度:1.332g/cm3
沸点:513.1ºC at 760mmHg
熔点:250-252ºC
闪点:264.1ºC
折射率:1.607

安全信息

RTECS号:XH5093600
WGK Germany:3
海关编码:2933990090

生产方法及用途

合成路线

  • 参考文献

    Journal of medicinal chemistry, , vol. 35, # 16 p. 3066 - 3075

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13C NMR : Predict


1H NMR : Predict


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