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化合物简介
Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.
基本信息
CAS:35354-74-6
中文别名:3\',5-二-2-丙烯基-1,1\'-联苯-2,4\'-二酚;阿帕替尼;3\',5\'-二-2-丙烯基-1,1\'-联苯-2,4\'-二酚;
英文别名:5,3\'-DIALLYL-2,4\'-DIHYDROXYBIPHENYL;3\',5-Diallyl-2,4\'-biphenyldiol;5,5\'-diallyl-2,4\'-dihydroxybiphenyl;5,3\'-diallyl-biphenyl-2,4\'-diol;3,3\'-DIALLYL-4,6\'-DIHYDROXYBIPHENYL;3\',5-Diallyl-2,4\'-dihydroxybiphenyl;3\',5-Diallylbiphenyl-2,4\'-diol;HONEYSUCKLEFLOWEREXTRACT;5,3\'-Diallyl-2,4\'-dihydroxybiphenyl;5,3\'-DIALLYL-2,4\'-DIHYDROXYDIPHENYL;
分子式:C18H18O2
分子量:266.334
精确质量:266.131
Psa:40.46
Logp:4.2218
中文别名:3\',5-二-2-丙烯基-1,1\'-联苯-2,4\'-二酚;阿帕替尼;3\',5\'-二-2-丙烯基-1,1\'-联苯-2,4\'-二酚;
英文别名:5,3\'-DIALLYL-2,4\'-DIHYDROXYBIPHENYL;3\',5-Diallyl-2,4\'-biphenyldiol;5,5\'-diallyl-2,4\'-dihydroxybiphenyl;5,3\'-diallyl-biphenyl-2,4\'-diol;3,3\'-DIALLYL-4,6\'-DIHYDROXYBIPHENYL;3\',5-Diallyl-2,4\'-dihydroxybiphenyl;3\',5-Diallylbiphenyl-2,4\'-diol;HONEYSUCKLEFLOWEREXTRACT;5,3\'-Diallyl-2,4\'-dihydroxybiphenyl;5,3\'-DIALLYL-2,4\'-DIHYDROXYDIPHENYL;
分子式:C18H18O2
分子量:266.334
精确质量:266.131
Psa:40.46
Logp:4.2218
编号系统
EINECS号:609-119-8
物化性质
外观与性状:暗棕色至白色细粉末带有令人愉快的气味,辛辣的和略苦味道
密度:1.107 g/cm3
沸点:400.1ºC at 760 mmHg
熔点:87.5ºC
闪点:184ºC
折射率:1.601
稳定性:Stable at normal temperatures and pressures.
储存条件:2-8ºC
密度:1.107 g/cm3
沸点:400.1ºC at 760 mmHg
熔点:87.5ºC
闪点:184ºC
折射率:1.601
稳定性:Stable at normal temperatures and pressures.
储存条件:2-8ºC
安全信息
安全说明:S26-S39-S61
危险类别码:R41; R51/53
WGK Germany:3
海关编码:2932999099
危险品运输编码:UN 3077 9/PG 3
危险品标志:Xi
危险标志:GHS05
信号词:Danger
危险性描述:H318
危险性防范说明:P280; P305 + P351 + P338
危险类别码:R41; R51/53
WGK Germany:3
海关编码:2932999099
危险品运输编码:UN 3077 9/PG 3
危险品标志:Xi
危险标志:GHS05
信号词:Danger
危险性描述:H318
危险性防范说明:P280; P305 + P351 + P338
生产方法及用途
合成路线
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参考文献
Tetrahedron, , vol. 66, # 40 p. 8029 - 8035
上游原料
下游产品
图谱
Predict 1H proton NMR








