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化合物简介
4-(2-Aminoethyl)benzenesulfonamide is used as the starting material in the synthesis of Des(5-methylpyrazinecarbonyl) trans-4-Methyl Glipizide; a degradation product of Glimepiride which is a sulfonylurea hypoglycemic agent and an antidiabetic. 4-(2-Aminoethyl)benzenesulfonamide is also used as a reagent in the synthesis of deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
基本信息
CAS:35303-76-5
中文别名:4-(2-氨基乙基)苯磺胺;4-(2-氨乙基)苯乙酰胺;
英文别名:4-Aminoethylbenzenesulfonamide;p-aminoethylbenzene sulfonamide;4-(2-AMINOETHYL)BENZENE SULFONMIDE;P-(2-AMINOETHYL)BENZENESULFONAMIDE;4-(2-Ethylamino) Benzene Sulfonamide;4-(2-Aminoethyl)Benzenesulfonamide;4-(2-Aminoethyl)benzene sulfonamide;2-(4-sulfamoyl-phenyl)-ethylamine;4-(2-Aminoethyl)benzesulfonamide;4-(2-aminoethyl)-benzenesulphonamide;
分子式:C8H12N2O2S
分子量:200.258
精确质量:200.062
Psa:94.56
Logp:2.3166
中文别名:4-(2-氨基乙基)苯磺胺;4-(2-氨乙基)苯乙酰胺;
英文别名:4-Aminoethylbenzenesulfonamide;p-aminoethylbenzene sulfonamide;4-(2-AMINOETHYL)BENZENE SULFONMIDE;P-(2-AMINOETHYL)BENZENESULFONAMIDE;4-(2-Ethylamino) Benzene Sulfonamide;4-(2-Aminoethyl)Benzenesulfonamide;4-(2-Aminoethyl)benzene sulfonamide;2-(4-sulfamoyl-phenyl)-ethylamine;4-(2-Aminoethyl)benzesulfonamide;4-(2-aminoethyl)-benzenesulphonamide;
分子式:C8H12N2O2S
分子量:200.258
精确质量:200.062
Psa:94.56
Logp:2.3166
编号系统
MDL号:MFCD00010301
物化性质
外观与性状:白色至灰白色结晶粉末
密度:1.293g/cm3
沸点:387.4ºC at 760mmHg
熔点:150-152°C(lit.)
闪点:188.1ºC
折射率:1.587
稳定性:Stable under normal temperatures and pressures.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
密度:1.293g/cm3
沸点:387.4ºC at 760mmHg
熔点:150-152°C(lit.)
闪点:188.1ºC
折射率:1.587
稳定性:Stable under normal temperatures and pressures.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
安全信息
安全说明:S45-S36/37/39-S26
WGK Germany:3
危险类别码:R22; R34
危险品运输编码:UN3259
海关编码:2935009090
危险类别:8
包装等级:III
危险品标志:C
WGK Germany:3
危险类别码:R22; R34
危险品运输编码:UN3259
海关编码:2935009090
危险类别:8
包装等级:III
危险品标志:C
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

13C NMR : in DMSO-d6

1H NMR : 400 MHz in DMSO-d6

Mass

IR : KBr disc

IR : nujol mull
