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  • (6-methoxynaphthalen-1-yl) trifluoromethanesulfonate

化合物简介

6-Methoxynaphth-1-yl trifluoromethanesulfonate is a useful synthetic intermediate. It is used to prepare analogs of GW 4064 with FXR agonists. It is also used to synthesize arylpiperazinylethylthienopyrancarboxamides as selective and potent 5-HT reuptake inhibitors with 5-HT1D antagonist activities.

基本信息

CAS:350584-53-1
中文别名
英文别名:Methanesulfonic acid,trifluoro-,6-methoxy-1-naphthalenyl ester;6-methoxy-1-naphthyltriflate;6-methoxy-1-naphthyl trifluoromethanesulfonate;6-methoxy-1-napthyl trifluoromethanesulfonate;6-methoxynaphthalen-1-yl trifluoromethanesulfonate;
分子式:C12H9F3O4S
分子量:306.258
精确质量:306.017
Psa:60.98
Logp:4.1576

编号系统

物化性质

安全信息

生产方法及用途

合成路线

  • 参考文献

    Hangeland, Jon J.; Friends, Todd J.; Doweyko, Arthur M.; Mellstroem, Karin; Sandberg, Johnny; Grynfarb, Marlena; Ryono, Denis E. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4579 - 4584

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1H NMR : Predict


13C NMR : Predict


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