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化合物简介
Chelerythrine is a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine). It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. It is also found in the plants Zanthoxylum clava-herculis and Zanthoxylum rhoifolium, exhibiting antibacterial activity against Staphylococcus aureus and other human pathogens.
基本信息
CAS:34316-15-9
中文别名:白屈菜红碱.白屈菜赤碱.白屈菜季铵碱;白屈菜赤碱,白屈菜季铵碱;白屈菜赤碱;
英文别名:[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-;Chelerythrine;Chelerythrin-Kation;Cheleritrine;Chelerythrin;Chelerythrine chloride;Broussonpapyrine;Chelerythrin chlorid;
分子式:C21H18ClNO4
分子量:383.825
精确质量:383.092
Psa:40.8
Logp:0.7206
中文别名:白屈菜红碱.白屈菜赤碱.白屈菜季铵碱;白屈菜赤碱,白屈菜季铵碱;白屈菜赤碱;
英文别名:[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-;Chelerythrine;Chelerythrin-Kation;Cheleritrine;Chelerythrin;Chelerythrine chloride;Broussonpapyrine;Chelerythrin chlorid;
分子式:C21H18ClNO4
分子量:383.825
精确质量:383.092
Psa:40.8
Logp:0.7206
编号系统
UNII:E3B045W6X0
物化性质
熔点:195-205ºC
安全信息
安全说明:S36/37
危险类别码:R20/21/22
海关编码:2933990090
危险品标志:Xn
危险类别码:R20/21/22
海关编码:2933990090
危险品标志:Xn
生产方法及用途
合成路线
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参考文献
Heterocycles, , vol. 20, # 8 p. 1535 - 1539
上游原料
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
