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化合物简介
Telatinib small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases. Telatinib is used therapeutically in patients with advanced solid tumors.
基本信息
CAS：332012-40-5
中文别名：
英文别名：Telatinib,BAY 57-9352,BAY 57-9352;4-[({4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide;Telatinib;Bay 57-9352;4-(4-chlorophenylamino)-7-(2-methylaminocarbonyl-4-pyridylmethoxy)furo-[2,3-d]pyridazine;4-(4-(4-chloro-phenylamino)-furo[2,3-d]pyridazin-7-yloxymethyl)-pyridine-2-carboxylic acid methylamide;4-((4-(4-chlorophenylamino)furo[2,3-d]pyridazin-7-yloxy)methyl)-N-methylpicolinamide;
分子式：C20H16ClN5O3
分子量：409.826
精确质量：409.094
Psa：102.17
Logp：4.4173
中文别名：
英文别名：Telatinib,BAY 57-9352,BAY 57-9352;4-[({4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide;Telatinib;Bay 57-9352;4-(4-chlorophenylamino)-7-(2-methylaminocarbonyl-4-pyridylmethoxy)furo-[2,3-d]pyridazine;4-(4-(4-chloro-phenylamino)-furo[2,3-d]pyridazin-7-yloxymethyl)-pyridine-2-carboxylic acid methylamide;4-((4-(4-chlorophenylamino)furo[2,3-d]pyridazin-7-yloxy)methyl)-N-methylpicolinamide;
分子式：C20H16ClN5O3
分子量：409.826
精确质量：409.094
Psa：102.17
Logp：4.4173
编号系统
MDL号：MFCD18251453
物化性质
密度：1.418 g/cm3
沸点：713.595ºC at 760 mmHg
闪点：385.368ºC
沸点：713.595ºC at 760 mmHg
闪点：385.368ºC
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
