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化合物简介
2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is used as a reagent to synthesize Piperidine receptor ligands, compounds that have potential antipsychotic activity. 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is also used as a reagent to synthesize Bromoperidol, a neuroleptic drug that is closely related to Haloperidol.
基本信息
CAS:3308-94-9
中文别名:2-(3-氯丙基)-2-(4-氟苯基)-1,3-二氧戊环;
英文别名:
分子式:C12H14ClFO2
分子量:244.69
精确质量:244.067
Psa:18.46
Logp:3.0443
中文别名:2-(3-氯丙基)-2-(4-氟苯基)-1,3-二氧戊环;
英文别名:
分子式:C12H14ClFO2
分子量:244.69
精确质量:244.067
Psa:18.46
Logp:3.0443
编号系统
MDL号:MFCD00020909
物化性质
外观与性状:透明无色至淡的黄色液体
密度:1.219
沸点:162-166 °C (15 mmHg)
闪点:147.4ºC
折射率:1.505-1.5075
水溶解性:insoluble
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
密度:1.219
沸点:162-166 °C (15 mmHg)
闪点:147.4ºC
折射率:1.505-1.5075
水溶解性:insoluble
稳定性:Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件:Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
安全信息
安全说明:S37/39-S26
危险类别码:R36/37/38
海关编码:2932999099
危险品标志:Xi
危险类别码:R36/37/38
海关编码:2932999099
危险品标志:Xi
生产方法及用途
用途
氟哌啶醇中间体。
氟哌啶醇中间体。
合成路线
-
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 12 p. 3622 - 3626
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
