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化合物简介
2-Methoxyphenylborornic Acid Pinacol Ester is used in the preparation of indole derivatives as selective inhibitors of all three members of the Pim kinase family. It is also used to prepare inhibitors of TGF-β1 and activin A signalling.
基本信息
CAS：321724-19-0
中文别名：5-嘧啶硼酸频哪醇酯;嘧啶-5-硼酸频哪醇酯;嘧啶-5-硼酸嚬哪醇酯;嘧啶-5-硼酸频哪酯;
英文别名：Pyrimidyl-5-boronic acid pinacolate;5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;5-Pyrimidineboronic acid pinacol ester;2-(5-pyrimidine)-4,4,5,5-tetramethyl-1,3-dioxaborolane;Pinacol ester pyrimidinyl-5-boronic acid;3,5-pyrimidylboronic acid pinacol ester;4,4,5,5-tetramethyl-2-pyrimidin-5-yl-1,3,2-dioxaborolane;5-(4,4,5,5-tetramethyl-(1,3,2)dioxaborolan-2-yl)-pyrimidine;Pyrimidine-5-boronic acid pinacol ester;5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)]pyrimidine;
分子式：C10H15BN2O2
分子量：206.049
精确质量：206.123
Psa：44.24
Logp：0.7758
中文别名：5-嘧啶硼酸频哪醇酯;嘧啶-5-硼酸频哪醇酯;嘧啶-5-硼酸嚬哪醇酯;嘧啶-5-硼酸频哪酯;
英文别名：Pyrimidyl-5-boronic acid pinacolate;5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;5-Pyrimidineboronic acid pinacol ester;2-(5-pyrimidine)-4,4,5,5-tetramethyl-1,3-dioxaborolane;Pinacol ester pyrimidinyl-5-boronic acid;3,5-pyrimidylboronic acid pinacol ester;4,4,5,5-tetramethyl-2-pyrimidin-5-yl-1,3,2-dioxaborolane;5-(4,4,5,5-tetramethyl-(1,3,2)dioxaborolan-2-yl)-pyrimidine;Pyrimidine-5-boronic acid pinacol ester;5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)]pyrimidine;
分子式：C10H15BN2O2
分子量：206.049
精确质量：206.123
Psa：44.24
Logp：0.7758
编号系统
MDL号：MFCD05155223
物化性质
密度：1.07g/cm3
沸点：308.9ºC at 760mmHg
熔点：60-66°C
闪点：140.6ºC
折射率：1.488
沸点：308.9ºC at 760mmHg
熔点：60-66°C
闪点：140.6ºC
折射率：1.488
安全信息
海关编码：2933599090
危险品标志：Xi
危险品标志：Xi
生产方法及用途
合成路线
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参考文献
WO2008/88881 A1, ; Page/Page column 38 ; WO 2008/088881 A1
上游原料
下游产品
图谱
13C NMR : Predict
