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  • 2-氨基-N-(2-氯-6-甲基苯基)噻唑-5-甲酰胺

    2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide

化合物简介

2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide, is a precursor in the synthesis of Dasatinib, a protein tyrosine kinase inhibitor, and also for 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives, used as potent and selective anti-tumor drugs.

基本信息

CAS:302964-24-5
中文别名:2-氨基-N-(2-氯-6-甲基苯基)-5-噻唑酰胺;
英文别名:2-amino-N-(2-cliloro-6-metliylplienyl)thiazole-5-carboxamide;2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide;2-AMINO-N-(2-CHLORO-6-METHYLPHENYL)THIAZOLE-5-CARBOXAMIDE;2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide;N-(2-chloro-6-methylphenyl)-2-amino-5-thiazolecarboxamide;2-aminothiazole-5-carboxylic acid (2-chloro-6-methylphenyl)amide;
分子式:C11H10ClN3OS
分子量:267.735
精确质量:267.023
Psa:96.25
Logp:3.5936

编号系统

EINECS号:608-455-2

物化性质

密度:1.474 g/cm3
沸点:362ºC at 760 mmHg
闪点:172.7ºC
折射率:1.714

安全信息

海关编码:2934100090

生产方法及用途

用途
达沙替尼的中间体。

合成路线

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图谱

13C NMR : Predict


1H NMR : Predict


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