Proadifen (SKF-525A) is a non-selective inhibitor of cytochrome P450 enzymes, preventing some types of drug metabolism. It is also an inhibitor of neuronal nitric oxide synthase (NOS), CYP-dependent (cytochrome P450-dependent) arachidonate metabolism, transmembrane calcium influx, and platelet thromboxane synthesis. Further documented effects include the blockade of ATP-sensitive inward rectifier potassium channel 8 (KIR6.1), and stimulation of endothelial cell prostacyclin production.

CAS：302-33-0
中文别名：
英文别名：HL 8727;Proadifeno [INN-Spanish];Proadifen [INN];BCTB;Ethyl aprofen;Proadifene [INN-French];Proadifenum [INN-Latin];proadifen;ACETIC ACID,PROPYLDIPHENYL-,2-(DIETHYLAMINO)ETHYL ESTER;
分子式：C23H31NO2
分子量：353.498
精确质量：353.235
Psa：29.54
Logp：4.6578

UNII：A510CA4CBT

密度：1.023g/cm3
沸点：460.8ºC at 760mmHg
闪点：132.3ºC
折射率：1.531