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5-Alpha-二氢皮质酮
(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
化合物简介
5α-Dihydrocorticosterone ((5α,11β)-11,21-dihydroxypregnane-3,20-dione; abbreviated as 5α-DHC, 5α-DHB) is a naturally-occurring, endogenous glucocorticoid steroid hormone and neurosteroid. It is biosynthesized from corticosterone by the enzyme 5α-reductase. DHC has central depressant effects and impairs long-term potentiation in animals.
基本信息
CAS：298-25-9
中文别名：
英文别名：5|A-Pregnane-11|A,21-diol-3,20-dione;5|A-Dihydrocorticosterone;5beta-Dihydrocorticosterone;5-Dihydrocorticosterone;5alpha-Dihydrocorticosterone;
分子式：C21H32O4
分子量：348.476
精确质量：348.23
Psa：74.6
Logp：2.7466
中文别名：
英文别名：5|A-Pregnane-11|A,21-diol-3,20-dione;5|A-Dihydrocorticosterone;5beta-Dihydrocorticosterone;5-Dihydrocorticosterone;5alpha-Dihydrocorticosterone;
分子式：C21H32O4
分子量：348.476
精确质量：348.23
Psa：74.6
Logp：2.7466
编号系统
物化性质
密度：1.175 g/cm3
沸点：508.5ºC at 760 mmHg
闪点：275.4ºC
折射率：1.548
蒸汽压：1.82E-12mmHg at 25°C
沸点：508.5ºC at 760 mmHg
闪点：275.4ºC
折射率：1.548
蒸汽压：1.82E-12mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
