7-Nitroindazole, or 7-NI, is a heterocyclic small molecule containing an indazole ring that has been nitrated at the 7 position. Nitroindazole acts as a selective inhibitor for neuronal nitric oxide synthase, a hemoprotein enzyme that, in neuronal tissue, converts arginine to citrulline and nitric oxide (NO). Nitric oxide can diffuse through the plasma membrane into neighbouring cells, allowing cell signalling, so nitroindazole indirectly inhibits this signalling process. Other inhibitors exist such as 3-bromo-7-nitroindazole, which is more potent but less specific, or NPA (N-propyl-L-arginine), which acts on a different site.

CAS：2942-42-9
中文别名：7-硝基-1氢吲唑;7-硝基-1H-吲唑;
英文别名：1H-Indazole,7-nitro;nitro-7 indazole;7-NI;7-nitroindazole;7-Nitroindazole;1H-Indazole, 7-nitro-;7-Nitro-1H-indazole;EINECS 220-934-4;
分子式：C7H5N3O2
分子量：163.133
精确质量：163.038
Psa：74.5
Logp：1.9943

MDL号：MFCD00022789

外观与性状：橙色-黄色固体
密度：1.525 g/cm3
沸点：383.3ºC at 760 mmHg
熔点：185-186°C
闪点：185.6ºC
折射率：1.74
水溶解性：slightly soluble
储存条件：-20ºC
蒸汽压：9.79E-06mmHg at 25°C

RTECS号：NK7962200
安全说明：S53-S22-S36/37/39-S45
WGK Germany：3
危险类别码：R60; R40
危险品运输编码：UN 2811 6.1/PG 3
海关编码：2933990090
危险品标志：T
信号词：Danger
危险标志：GHS06, GHS08
危险性描述：H301; H319; H351; H360
危险性防范说明：P201; P281; P301 + P310; P305 + P351 + P338; P308 + P313