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化合物简介
6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone, a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
基本信息
CAS：2921-57-5
中文别名：甲基泼尼松龙琥珀酸;琥珀酸甲泼尼龙;甲泼尼松龙琥珀酸酯;
英文别名：METHYLPREDNISOLONE SODIUM SUCCINATE;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;Solumedrol;methylprednisolone hemisuccinate esters;Methylprednisolone hemisuccinate;methylprednisolone succinate;EINECS 220-863-9;Urbason-Soluble;Methylprednisolone hydrogen succinate;6-methylprednisolone-21-hemisuccinate;METHYLPREDNISOLONE HEMISUCCINATE;methylprednisolone 21-hemisuccinate;UNII-5GMR90S4KN;
分子式：C26H34O8
分子量：474.543
精确质量：474.225
Psa：138.2
Logp：2.2193
中文别名：甲基泼尼松龙琥珀酸;琥珀酸甲泼尼龙;甲泼尼松龙琥珀酸酯;
英文别名：METHYLPREDNISOLONE SODIUM SUCCINATE;4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;Solumedrol;methylprednisolone hemisuccinate esters;Methylprednisolone hemisuccinate;methylprednisolone succinate;EINECS 220-863-9;Urbason-Soluble;Methylprednisolone hydrogen succinate;6-methylprednisolone-21-hemisuccinate;METHYLPREDNISOLONE HEMISUCCINATE;methylprednisolone 21-hemisuccinate;UNII-5GMR90S4KN;
分子式：C26H34O8
分子量：474.543
精确质量：474.225
Psa：138.2
Logp：2.2193
编号系统
UNII：5GMR90S4KN
物化性质
密度：1.33g/cm3
沸点：689.6ºC at 760mmHg
闪点：230.7ºC
折射率：1.593
蒸汽压：5.28E-22mmHg at 25°C
沸点：689.6ºC at 760mmHg
闪点：230.7ºC
折射率：1.593
蒸汽压：5.28E-22mmHg at 25°C
安全信息
海关编码：2942000000
生产方法及用途
合成路线
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参考文献
Journal of Pharmaceutical Sciences, , vol. 73, # 5 p. 604 - 610
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
