化学科研者一站式服务平台
化合物简介
Nicotine-1’-N-oxide is a derivative of Nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as metabolites of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
基本信息
CAS:2820-55-5
中文别名:
英文别名:1-chloroacetyl-L-proline;nicotine N-oxide;N-chloroacetyl-L-proline;nicotine nitrogen oxide;
分子式:C10H14N2O
分子量:178.231
精确质量:178.111
Psa:28.7
Logp:1.8197
中文别名:
英文别名:1-chloroacetyl-L-proline;nicotine N-oxide;N-chloroacetyl-L-proline;nicotine nitrogen oxide;
分子式:C10H14N2O
分子量:178.231
精确质量:178.111
Psa:28.7
Logp:1.8197
编号系统
UNII:8WQ7L5T6TJ
物化性质
密度:1.15g/cm3
沸点:347.9ºC at 760mmHg
闪点:164.2ºC
折射率:1.589
稳定性:Very Hygroscopic
储存条件:Refrigerator, Under Inert Atmosphere
蒸汽压:5.22E-05mmHg at 25°C
沸点:347.9ºC at 760mmHg
闪点:164.2ºC
折射率:1.589
稳定性:Very Hygroscopic
储存条件:Refrigerator, Under Inert Atmosphere
蒸汽压:5.22E-05mmHg at 25°C
安全信息
海关编码:2933990090
生产方法及用途
合成路线
-
参考文献
Kokatla, Hari Prasad; Thomson, Paul F.; Bae, Suyeal; Doddi, Venkata Ramana; Lakshman, Mahesh K. Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7842 - 7848
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
Mass spectrum (electron ionization)








